New daily weight-loss pill shows success at clinical trial

theguardian.comPublished: 4/17/2025

Summary

A groundbreaking trial of a daily weight-loss pill, orforglipron, has shown remarkable success in helping individuals lose significant weight and improve blood sugar levels. Conducted across multiple countries, the study involved 559 participants with type 2 diabetes, who lost an average of 7.3kg over nine months on the highest dose. The pill, a GLP-1 agonist available as a daily tablet, also reduced blood sugar levels, potentially offering a new treatment option for obesity and diabetes. Eli Lilly plans to seek approval for its use in weight management and diabetes, with results expected to be published later this year.