Scientists use live human brain tissue to speed up hunt for dementia cure

theguardian.comPublished: 4/30/2025

Summary

Scientists have made a groundbreaking advance in studying Alzheimer’s disease by using living human brain tissue. A British team exposed healthy brain tissue from NHS patients to toxic amyloid beta proteins, collected from individuals who died of Alzheimer’s, and observed the damage in real-time. This method allows for direct observation of disease progression, offering a valuable tool to test new treatments and understand how amyloid-beta disrupts brain function with minimal changes needed for proper operation. The research is supported by significant backing from charities and foundations, highlighting its potential impact on finding effective cures.