How the brain, with sleep, maps space

technologyreview.comPublished: 4/22/2025

Summary

Mice begin with a basic understanding of mazes, lacking detailed spatial awareness initially. Over time, they refine their cognitive maps during sleep, a process that involves place cells firing over days and collaboration with other neurons to create accurate spatial representations. Sleep plays a crucial role in enhancing these maps, as evidenced by experiments showing improved memory maps when mice rest compared to those who remain awake. This highlights the importance of sleep in learning and the intricate teamwork between different brain regions involved in spatial navigation.