Psychedelics May ‘Reset’ the Brains of People With Depression and Anxiety

vice.comPublished: 5/9/2025

Summary

Psychedelics like psilocybin and MDMA show promise as new treatments for mental health issues such as PTSD and depression, according to a study linking brain cells called astrocytes to chronic inflammation. The research highlights that these stress-sensitive cells become activated under prolonged stress, disrupting communication between neurons and immune cells. Introducing psychedelics has shown in both mice models and humans with depressive disorder that they can reduce this inflammation, potentially aiding in the alleviation of symptoms associated with mental health conditions tied to inflammation.