$101m longevity research prize aims to ‘shatter the limits’ on ageing

theguardian.comPublished: 5/11/2025

Summary

The XPrize Healthspan, the largest ever prize for aging research, is seeking cutting-edge solutions to rejuvenate three critical systems—muscles, cognition, and immune function—to extend healthy lifespan by 10-20 years. The competition offers $101 million in prizes, with a winning solution expected to be scalable within a year and accessible at low cost. Teams from diverse backgrounds are proposing innovative approaches, including biologics, nutraceuticals, lifestyle interventions, and personalized dietary strategies like wheatgrass and niacin mononucleotide (NMN), emphasizing diet, exercise, and behavior as central elements for healthy aging.